张宇飞,男,汉族,内蒙古呼和浩特市和林格尔县人,bat365官方网站高层次人才(第五层次),主要研究方向:病原微生物致病机理及新型疫苗开发。主持国家科技部重点研发计划揭榜挂帅项目子项目1项;主持国家科技部重点研发计划新型冠状病毒感染的肺炎疫情应急专项子项目1项。主要代表成果:在柳叶刀子刊《EBioMedicine》发表ESI前1%高被引论文1篇。以第一作者在病毒学领域内重点刊物EBioMedicine、Journal of Virology、Journal of IinfectiousDiseases等杂志上发表英文SCI论文8篇。参编专业著作1部,授权发明专利5件。目前担任Animal Research and One Health (AROH)青年编委,The American Society for Microbiology(ASM)Journals,Frontiers Cellular and Infection Microbiology审稿人员。
教育及工作经历:
2007.09-2011.06bat365官方网站动物科学与医学学院动物医学
2011.09-2016.06关于在线登录入口基础兽医学硕博连读
2016.07-2019.04中国农业科学院特产研究所特种经济动物研究室助理研究员
2019.06-2022.06华中农业大学动物科学技术学院、动物医学院预防兽医学系博士后
发表论文:
1.Zhang Y, Huang K, Wang T, Deng F, Gong W, Hui X, Zhao Y, He X, Li C, Zhang Q, Chen X, Lv C, Lin X, Yang Y, Sun X, Shi Z, Chen H, Zou Z, Jin M. SARS-CoV-2 rapidly adapts in aged BALB/c mice and induces typical pneumonia.J Virol.2021 Mar 10;95(11):e02477-20.(IF=6.5中科院二区top高被引论文)
2.Huang K#,Zhang Y#, Hui X, Zhao Y, Gong W, Wang T, Zhang S, Yang Y, Deng F, Zhang Q, Chen X, Yang Y, Sun X, Chen H, Tao YJ, Zou Z, Jin M. Q493K and Q498H substitutions in Spike promote adaptation of SARS-CoV-2 in mice.EBioMedicine.2021 May;67:103381.(IF=11.2中科院一区top高被引论文)
3.Zhang Y, Gao J, Huang K, Zhao Y, Hui X, Wang T, Hu C, Sun X, Yang Y, Wu C, Chen X, Zou Z, Zhao LZ, Jin M. SARS-CoV-2 Infection Causes Hyperglycemia in Cats. J Infect Dis. 2022 Nov 1;226(9):1568-1576. doi: 10.1093/infdis/jiac143. PMID: 35639863; PMCID: PMC9047237.(IF=7.7中科院二区top)
4.Zhang Y,Zhu Y, Cao X, Zhang G, Liu S. Cell adhesion function was altered during the seasonal regression of the seminiferous epithelium in the mink species Neovison vison. J Anim Sci. 2023 Jan 3;101:skad190. doi: 10.1093/jas/skad190. PMID: 37282598; PMCID: PMC10276646.(IF=3.3中科院二区top)
5.Yufei Zhang; Li Yang; Jiali Zhang; Kun Huang; Xiaomei Sun; Zhong Zou; Meilin Jin.
Oral or intranasal immunization with recombinant Lactobacillus plantarum displaying head domain of Swine Influenza A virus hemagglutinin protects mice from H1N1 virus. Microb Cell Fact. 2022 Sep 9;21(1):185. doi: 10.1186/s12934-022-01911-4. PMID: 36085207; PMCID: PMC9461438.(IF=6.4中科院二区)
6.Yufei Zhang; Baozeng Xu. Involvement of testicular N-glycoproteome heterogeneity in seasonal spermatogenesis of the American mink (Neovison vison). Front Vet Sci. 2022 Nov7;9:1001431. doi: 10.3389/fvets.2022.1001431. PMID: 36406079; PMCID: PMC9672844.(IF=3.5中科院二区)
7.ZHANG Yu-fei, Shi Jing, LIU Shu-ying. Recent advances in the study of active endogenous retrovirus envelope glycoproteins in the mammalian placenta [J].VIROLOGICA SINICA2015, 30 (4): 239-248.(IF=6.9中科院二区)
8.Zhang Y, Shi J, Liu S. Establishment and Characterization of a Telomerase-Immortalized Sheep Trophoblast Cell Line[J].BioMed research international, 2016, 2016.(IF=3.2中科院三区)
9.张宇飞,曹满园,王丽英,赵伟刚,李晓霞,常彤,许保增.梅花鹿激活素A重组蛋白真核表达、纯化及其生物活性的测定[J].中国农业科学,2020,53(05):1058-1070.
10.张宇飞,曹满园,王丽英,赵伟刚,许保增.水貂睾丸退化期间TGFB家族生长因子及其受体基因表达量的变化[J].兽类学报,2019,39(02):191-201.
11.张宇飞,李晓霞,王士勇,等.北极狐及乌苏里貉抑制素α亚基基因克隆及生物信息学分析[J].中国畜牧兽医,2017,(12):3391-3400.
12.张宇飞,石晶,刘淑英. enJSRV囊膜蛋白及其受体的瞬时表达与绵羊绒毛膜滋养层细胞融合的诱导研究[J].畜牧兽医学报2015, 46 (11),1924-1933。
13.张宇飞,刘月,刘淑英,等.绵羊肺腺瘤病毒pEGFP-C1/exJSRV-env构建及引起NIH3T3细胞恶性转化的研究[J].病毒学报, 2014, 30(3):268-276。
14.张宇飞,刘月,刘淑英,等.靶向enJSRV-env基因shRNA真核表达质粒的构建及其干扰效率的测定[J].中国兽医科学, 2013, 43(01):53-59。
15.张宇飞,石晶,刘淑英.绵羊子宫内膜上皮细胞的培养鉴定及瞬时表达enJSRV囊膜蛋白及其受体Hyal2[J].中国兽医科学,2015, 45 (10):1189-1195。
授权发明专利:
1金梅林;张宇飞;黄坤;杨丽;邹忠;赵亚;回显峰;王婷;孙小美;陈西;高嗍;一种新型冠状病毒鼠适应株SARS-CoV-2/WBP-1及应用, 2020,中国, ZL202010881426.8 (发明)
2张宇飞;许保增;曹满媛;赵伟刚;李晓霞;刁云飞;曹新燕;赵蒙;狐亚科激活素A蛋白及其制备与应用, 2018-10-26,中国,ZL201811258395.X(发明)
3张宇飞;王丽英;许保增;王士勇;孟庆江;朱海瑛;曹新燕;常彤;水貂激活素B蛋白及其制备与应用, 2018-10-26,中国,ZL201811258408.3(发明)
4许保增;张宇飞;王丽英;曹满媛;赵伟刚;杨溢峰;魏海军;鹿亚科激活素A蛋白及其制备与应用2018-10-26,中国,ZL201811261653.X(发明)
5赵建军;陶荣珊;张宇飞;陈杰;刘梦佳;基于水貂源Nectin4受体的犬瘟热病毒敏感细胞系、制备方法和应用, 2019-5-20,中国, ZL201910421114.6 (发明)